inflammation response – Communicable Diseases Research

Differential transcriptomic landscapes of multiple organs from SARS-CoV-2 early infected rhesus macaques

SARS-CoV-2 초기 감염된 붉은털 원숭이의 여러 기관의 차등 전사체 풍경

Article

Published on 2022-12-012022-09-11
Journal: Protein & Cell
[Category] COVID19(2023년), SARS, 유전자 메커니즘, 진단,

Evaluation of zinc, copper, and Cu:Zn ratio in serum, and their implications in the course of COVID-19

Research article

Published on 2022-05-012022-10-05
Journal: Journal of trace elements in medicine and biology
[Category] 바이오마커,

MS-based targeted profiling of oxylipins in COVID-19: A new insight into inflammation regulation

COVID-19에서 MS 기반 옥시리핀 표적 프로파일링: 염증 조절에 대한 새로운 통찰력

Observational Study

Published on 2022-02-202022-09-12
Journal: Free radical biology & medicine
[Category] COVID19(2023년), MERS, SARS, 바이오마커, 임상, 진단,

[키워드] analysed Anti-inflammatory AUC Biomarker canonical characterisation characteristic collected computation COVID-19 COVID-19 patients cytokine Cytokines dataset Fisher ICU patient ICUs Inflammation Inflammation regulation inflammation response inflammatory cascade inflammatory mediator intensive care unit Lipid lipid mediator Lipid mediator class switching magnitude Oxylipins Patient PCA pilot study plasma plasma concentration platform Pneumonia principal component analysis pro-inflammatory status Regulation respond resulting retrospective risk ROC ROC Curve selected severe COVID-19 severity predictors shown switching targeting the cytokine storm UHPLC-MS/MS. university with COVID-19
[DOI] 10.1016/j.freeradbiomed.2022.01.021 PMC 바로가기 [Article Type] Observational Study

Cannabidiol and Terpene Formulation Reducing SARS-CoV-2 Infectivity Tackling a Therapeutic Strategy

Immunology

Published on 2022-02-152022-11-01
Journal: Frontiers in Immunology
[Category] COVID-19, COVID19(2023년), SARS,

[키워드] A549 alveolar analyzed Anti-inflammatory Antiviral approach Caco-2 cannabidiol cannabis CBD - cannabidiol cell line cell lines cell receptor cellular Colon Combination COVID-19 Effectiveness endocannabinoid system (ECS) epithelial essential oil (EO) evaluate evaluated Formulation formulations GC-MS HaCaT Health Host HPLC human cell lines Impact in vitro study Infectivity Inflammation inflammation response Interaction kidney knowledge Origanum purified reduce reducing SARS-CoV-2 Strategy terpene terpenes Therapeutic compounds Therapeutic strategies Therapeutics therapy thymus virus infectivity Virus life cycle Wuhan, China
[DOI] 10.3389/fimmu.2022.841459 PMC 바로가기 [Article Type] Immunology

SARS‐CoV‐2 triggered oxidative stress and abnormal energy metabolism in gut microbiota

Original Article

Published on 2022-01-172022-10-30
Journal: MedComm
[Category] COVID-19,

[키워드] ABC accompanied Actinomyce alteration Amino acid analyzed annotation Antiviral Bacteria Bacteroide Biomarkers Butyrate characteristic characterized collected controls correlated COVID‐19 COVID‐19 patient COVID‐19 Critical Defense disease severity energy metabolism ENhance Escherichia coli exacerbate expression Fecal sample functions genes encoding Gut gut microbiota indicated Infection inflammation response Inflammatory intestinal flora KEGG Kyoto mechanism metabolism metagenome metagenomic metatranscriptome metatranscriptomic microbe Microbiome Neutral Ontology oxidative stress pathogen pathway positively correlated progression reduced SARS‐CoV‐2 SARS‐CoV‐2 virus SARS‐CoV‐2 selected Sequencing severity significantly Specific sphingolipids Streptococcus sugar suggested triggered upregulated upregulation was performed
[DOI] 10.1002/mco2.112 PMC 바로가기 [Article Type] Original Article

Multi-omic approach identifies a transcriptional network coupling innate immune response to proliferation in the blood of COVID-19 cancer patients

Multi-omic 접근법은 COVID-19 암 환자의 혈액에서 증식에 대한 타고난 면역 반응을 결합하는 전사 네트워크를 식별합니다.

Article

Published on 2021-10-292022-09-12
Journal: Cell Death & Disease
[Category] MERS, 임상, 진단,

[키워드] Alter alteration analyses Analysis analyzed approach Blood Cancer cancer patient Cancer patients cancer type CD4 CD8 Cell cell population central memory circulating clinical co-morbidities Cohort conducted contribute controls COVID-19 COVID-19 disease COVID-19 patient cytokine Cytometry Diseases Donor eight elevated enrichment analysis expression Gene Expression Genes highlight homeostasis identify IL-13 IL-6 IL-8 Immune cell immune function immune system immunological parameter immunology Infection Infectious diseases inflammation response innate immune response investigated IP-10 modulated mononuclear cell mortality rates multiplex natural killer outcome Patient PBMC PBMCs performed Peripheral blood plasmablast pro-inflammatory factor proliferation reduced Regulation SARS-COV-2 infection serum cytokine Signaling solid cancers Stage subpopulation T cell T lymphocyte transcriptional worsened
[DOI] 10.1038/s41419-021-04299-y PMC 바로가기 [Article Type] Article

Epicardial fat inflammation response to COVID-19 therapies

COVID-19 치료법에 대한 심외막 지방 염증 반응

Article

Published on 2021-09-012022-09-12
Journal: Obesity (Silver Spring, Md.)
[Category] 진단,

The Positive Role of Tai Chi in Responding to the COVID-19 Pandemic

Communication

Published on 2021-07-132022-10-29
Journal: International Journal of Environmental Research an
[Category] COVID-19, SARS,

Correlation of Low Levels of α -1 Antitrypsin and Elevation of Neutrophil to Lymphocyte Ratio with Higher Mortality in Severe COVID-19 Patients

중증 COVID-19 환자에서 낮은 수준의 α-1 항트립신과 호중구 대 림프구 비율 상승과 사망률의 상관관계

Observational Study

Published on 2021-04-282022-09-10
Journal: Mediators of Inflammation
[Category] MERS, SARS, 유전자 메커니즘, 임상,

[키워드] accounted Admission alterations antitrypsin arterial oxygen saturation blood count blood sugar C-reactive protein CBC Chain Reaction cohort study Comorbidities complete blood count COVID-19 COVID-19 illness COVID-19 patient CRP CRP level CRP values dysregulated immune response dysregulation Elevation erythrocyte sedimentation erythrocyte sedimentation rate ESR etiology explanation form Glutamate groups Hospitalization hospitalized patient hospitalized patients hyperinflammation immune dysregulation immune response immunomodulatory effect individual Individual differences inflammation response involved Level lymphocyte marker mechanism mortality rate MOST neutrophil NLR not significantly different O2sat Observational cohort study Oxaloacetate oxygen oxygen saturation patients PCR percentage percentages plasma protein polymerase chain polymerase chain reaction positive COVID-19 Prevalence pyruvate random Ratio RBC Result retrospective sedimentation rate serum Serum level severe COVID-19 severe COVID-19 illness severe COVID-19 patient severe COVID-19 patients severe forms of COVID-19 severe symptoms severity SGOT SGPT sugar the patient troponin troponin level troponin levels with COVID-19
[DOI] 10.1155/2021/5555619 PMC 바로가기 [Article Type] Observational Study

Genomic characterization and evolution of SARS-CoV-2 of a Canadian population

Research Article

Published on 2021-03-042022-10-28
Journal: PLoS ONE
[Category] COVID-19, SARS,